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Statins Statins are lipid-lowering drugs that prevent cholesterol synthesis by inhibiting 3-hydroxy-3-methylglutaryl-CoA reductase, commonly used in treating hypercholesterolemia and cardiovascular-related diseases [151]

Notably, compared with the control group (baseline: 89.8% of parasites expressing iron utilization-related genes among all parasites), the proportion of parasites expressing these genes increased to 96.1% after 3 h of DHA treatment and 96.0% after 9 h of DHA treatment

In particular, it remains unknown whether ferroptosis inducers can simultaneously induce ferroptosis of cancer cells and immune cells to comprise the bodys immune function, and how ferroptosis inducers can modulate different immune cells to enhance or weaken the bodys immune response

Therefore, targeting cellular oxidative stress, i.e., inhibiting lipid peroxidation, could be a way to inhibit ferroptosis

1A - STOT SE 3 target_organs Respiratory system 3 - Flammable liquids flash_point_f -14.8 F - closed cup flash_point_c -26 C - closed cup ppe Faceshields, Gloves, Goggles :

doi: 10.18632/aging.202409, 20