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En cuanto a los estudios complementarios, destacaron los hallazgos siguientes: la bioqumica sangunea, incluyendo medicin de colesterol total y sus fracciones as como triglicridos, fue repetidamente normal, salvo incrementos intermitentes de CPK total (valores entre 230 y 380 U/l, con porcentaje de fraccin MB inferior al 10% del total) con aldolasa normal, mnimos incrementos de LDH y en una ocasin un valor de ALT de 70 U/l

Cai J, Liang X, Sun Y, et al

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Filgotinib as Induction and Maintenance Therapy for Ulcerative Colitis (SELECTION): A Phase 2b/3 Double-Blind, Randomised, Placebo-Controlled Trial. Lancet 397, no

Overholtzer, A

doi: 10.1016/j.jbc.2023.105247 84 YokomizoTNakamuraMShimizuT