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PMID: 7987248

Methylcobalamin : A naturally occurring, bioactive form of B12 preferred for neurological conditions

Higher NAD enhances SIRT1 activity, promoting fat oxidation and mitochondrial remodeling via PGC-1 pathwaysmechanisms consistent with improved endurance and recovery potential (Cant et al., Cell Metabolism

Such findings led scientists to label AOD-9604 as the worlds first drug with a metabolic mechanism of action for obesity meaning it works by accelerating fat metabolism rather than suppressing appetite