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Conclusions This study found that cumulative tobacco exposure is associated with raised systolic blood pressure in Chinese population, especially in the minority population

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In addition, atherosclerotic plaques occluding the coronary arteries may break apart, thus inflaming the arterial walls and causing the release of other chemical mediators such as prostaglandins, leukotrienes and substance P that sensitize pain receptors and amplifies the magnitude of the chest pain

[16] [13] The altering effects are due to compounds in tobacco smoke and not to nicotine

INTRODUCTION Smoking and other forms of tobacco or nicotine use, including the use of e-cigarettes, induce biomarkers of cardiovascular disease (CVD) risk 1