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This coincided with in vitro inhibition of RBL-2H3 mast cell degranulation upon formononetin treatment (10, 20, 40 M) with suppression of morphological changes and cytoskeletal decomposition, mediated by NF-B signaling

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Zhang M, Zhang H, Li H, Lai F, Li X, Tang Y, et al

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ESMO Open 7:100365

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These studies highlight that the phosphorylation of STAT3 can inhibit the SMAD3-dependent gene expression

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