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The impact of APOE on neuronal energy metabolism has already been shown

Tofacitinib, baricitinib, and ruxolitinib are among the JAK inhibitors currently investigated to determine whether they can treat COVID-19 (e.g., NCT-04332042, NCT-04348695, NCT-04321993, and NCT-04348695) (Peterson et al., 2020)

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His current translational research efforts focus on developing a novel small molecule treatment of lung cancer (Stat-3 inhibitor oncrasin-72) and revealing the prognostic and therapeutic role of the biomarker PKR/eIF2 a

Genetic susceptibility plays a key role

Oxidative stress and mitochondrial dysfunction are considered central features of neurodegenerative diseases [26], and the long-term use of KD may positively affect mitochondrial function through several mechanisms