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In contrast, we suggest that clinicians should examine the IO&NS pathophysiology, their sequelae, and the possible precipitating and maintaining factors (for example, infections) in any given patient

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Taylor AD, Cowell AM, Flower J, Buckingham JC

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There are diagnostic difficulties in this set of patientsthe simplified score may classify a significant proportion of these patients as probable (5083%) [5, 169,170,171,172,173], IgG may be normal in up to 53% [167,168,169,170,171,172,173], and 043% of these patients are seronegative [5, 167,168,169,170,171,172,173]