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Reported side effects of injectable GHK-Cu include: Mild redness or irritation at the injection site Occasional bruising Mild nausea (rare) Temporary skin flushing Reported side effects of topical GHK-Cu include: Skin sensitivity or redness (usually mild and transient) Allergic reaction in individuals with copper sensitivity (rare) GHK-Cu doesn't affect hormone levels, blood sugar, blood pressure, or any major organ system function at therapeutic doses