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[DOI] [PMC free article] [PubMed] [Google Scholar] 151.Mumtaz G.R., Weiss H.A., Thomas S.L., Riome S., Setayesh H., Riedner G., Semini I., Tawil O., Akala F.A., Wilson D., et al

In vitro studies indicate that exposure to PS-MPs triggers NF-B pathway activation in microglia, resulting in an overproduction of IL-1, TNF-, and nitric oxide (NO) 37

In diffuse TBI models, the expansion of atypical astrocytic regions positively correlates with seizure frequency (244)

This spike in circulating cortisol can trigger the gut-brain axis via the vagus nerve, signaling the enteric nervous system to accelerate motility and cause sudden bathroom urgency

Evidence for reductive activation of the oxy-ferrous complex by tetrahydrobiopterin

Each works by mimicking natural GLP-1 but with modifications that dramatically extend the half-life