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SKU: 34001901072
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Description

Sphingomyelin accumulation occurs in Niemann-Pick diseases (NPD) type A and B and causes severe disturbance in cell homeostasis [75]

10.3389/fphar.2014.00196 5 AstaritaJ

This work was supported by the Italian Ministry of Health (Ricerca Corrente)

10.1042/BST20140118 191

Metastatic or primary lung tumours were shown to rely on enhanced expression of NFS1 to maintain the supply of FeS clusters as co-factors of multiple essential proteins and enzymes in the cell that are exposed to (damaging) high oxygen concentrations