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The overexpression of wild-type HSPA9 reverses peroxisome loss, whereas an HSPA9 mutant associated with PD fails to rescue HSPA9-depleted neuronal cells 74

The same study found that the absence of Oxalobacter formigenes correlated with higher plasma oxalate levels.[ref] The kidneys play a key role in maintaining the balance of oxalates in the body

It is therefore an object of the invention to provide for a safe, effective and versatile approach for carrying cargo such as small molecules, peptides, proteins and nanocontaines (such as liposomes) containing drugs and genes across the cell membrane and across a blood-tissue barrier such as the blood-brain barrier for inter alia CNS drug targeting using glutathione transport receptors

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A repetition time of 1.6 s was used for recovery of longitudinal magnetization between scans, and a number of 128 accumulations was set, resulting in a total measurement time of 14 min