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Protonation states of amino acids are highly susceptible to changes in environmental pH, and thus, preparing the protein at pH 7.0 and 5.5 generates different acid dissociation constants, which ultimately affect the bond-forming tendencies of residues

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This remarkable ability makes glutathione a key player in the body's defense system, helping to maintain cellular integrity and function

doi: 10.3732/AJB.94.12.1992 232 Salas-AraizaM

1 2 3 4 5 6 Koeth, R

EGCG reportedly suppresses DNMT activity via radical scavenging and antioxidant mechanisms, leading to demethylation and upregulated expression of tumor suppressor genes P16 and P21, ultimately inducing apoptosis and inhibiting tumorigenesis