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22 In two randomized controlled trials, one with 46 and the other 63 subjects with obesity and tinnitus, a diet and exercise weight loss intervention was found to reduce tinnitus severity and improve quality of life, particularly in participants who lost 5% or more of their body weight

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(This might relate to propofols inhibition of NMDA receptors, which blocks tolerance and withdrawal.) Propofol suppresses respiration, which can be helpful among ventilated patients to reduce ventilator dyssynchrony

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Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms

(Nature, 2014) used an antisense oligonucleotide to knock down NNMT in mice and reported reduced fat-mass gain, better glucose tolerance, and lower liver triglycerides the founding paper for the whole NNMT-inhibitor field