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Esworthy RS, Aranda R, Martn MG (2001) Mice with combined disruption of Gpx1 and Gpx2 genes have colitis

The presence of the two signature features of an aggregation prone protein, namely a hydrophobic region and a sequence with a strong propensity to adopt a beta pleated sheet structure make -synuclein an ideal candidate for fibrillation

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The progression to clinical decompensation in cirrhosis is linked to SIBO

GSH depletion can trigger ferroptosis, which has been exploited in cancer treatments [17], and supplementation with GSH is utilized by glutathione peroxidase 4 (GPX4) to prevent lipid peroxidation, in turn inhibiting ferroptosis

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