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Description

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Marzloff G, Cansev M, Wurtman RJ

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Neurodegeneration and demyelination in multiple sclerosis

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Three-dimensional segregation of supramolecular activation clusters in T cells

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Once internalized by the cell through the folate receptor (RFC1), MTX undergoes sequential glutamylation by folyl-polyglutamate synthase (FPGS), thus becoming MTX polyglutamates (MTX-PG 2-6 )

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10.1155/2019/5080843 93 SunK.JingX.GuoJ.YaoX.GuoF

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