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These include chemical modifications of siRNA to improve its stability and reduce protein binding, packaging siRNA into nanoparticles to promote delivery and inhibit non-target cell uptake, and using tissue-specific targeting ligands to optimize siRNA specificity and prevent off-target effects [35]

Mice are killed at 28 weeks after exposure to Benzo[a]pyrene

10.1016/j.mimet.2009.09.012 J

Purification and concentration of DNA from aqueous solutions

Ni et al., 2020)

Emerging research in proteomics, metabolomics, and integrative multi-omics is helping to characterize its biological mechanisms, although this field remains in an early stage, enabling the development of improved diagnostics and targeted therapeutics