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These compounds play a pivotal role in modulating the gut microbiome, which in turn influences intestinal health and liver detoxification through complex molecular mechanisms and signaling pathways (121, 123)

Additionally, more than one receptor type and different G-protein coupling of neuropeptide receptors in different tissues lead to variable effects of the same neuropeptides in different tissues/cell types [24,25,26,27,28,29,30,31,32,33,34,35,36]

Available from: [DOI] [PMC free article] [PubMed] 9.Dejeu IL, Vica LG, Marian E, Ganea M, Fren OD, Maghiar PB et al

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