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Coenzyme Q10 (CoQ10) Coenzyme Q10 is a powerful antioxidant that protects the skin from oxidative damage and supports cellular energy production for optimal skin health

Open Access Rheumatology: Research and Reviews 9:6779 Berger J, Moller DE (2002) The mechanisms of action of PPARs

Sigma-Aldrich, 87917) and MitoSOX Red (ThermoFisher, M36008)

Phylogenetic analysis categorizes GPXs into three evolutionary groups, GPX1/GPX2, GPX3/GPX5/GPX6 and GPX4/GPX7/GPX8, with only GPX1-4 and GPX6 identified as selenoproteins [10,12]

It was observed that most of these natural substances that were selected and discussed in this review work to protect the dopaminergic neurons in the substantia nigra region of the brain, as they activate the mitochondrial function in these cells