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doi: 10.1177/092464 79251353384 216

Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway

The abnormal deposition of ECM forms the basis for intestinal wall thickening and stenosis, with transforming growth factor- (TGF-)/Smad signaling playing a significant role