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The active sites of GPx7 and GPx8 consist of a catalytic tetrad including Cys, Trp, Asn, and Gln/Ser residues

And we love each of those things equally

The second-order reaction rate constant between RT and GSH is 7.5 M 1 s 1 , while the same rate constant for our previously reported ThiolQuant Green probe and GSH is 0.15 M 1 s 1 , which is 50 times slower than RT (Table 2)

(2003) Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2

Plants strive to precisely control this state during biotic stress, as optimal redox levels enable proper induction of defense mechanisms against plant viruses