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CS exposure causes both the release of proinflammatory cytokines and a large number of reactive oxygen species (ROS), leading to the damage of both oxidative and aggravating inflammation, thus resulting in the morphological changes in emphysema after long-term exposure

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9.32 Enzymatic Functions In addition to its antioxidant function, vitamin C is also a cofactor for a number of enzymes

Excess copper reacts easily with oxygen, creating reactive oxygen species (ROS) tiny sparks that damage cell membranes and proteins if not neutralized in time

(216) utilized C57BL/6J mice to induce a model of SSc, confirming that mesenchymal stem cells (MSCs) alleviate SSc symptoms by modulating the balance of the gut microbiota