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The buyer told the store clerk his or her symptoms and the clerk selected the appropriate numbered treatments for the store display

While the prevalence of smoking in the US has decreased from approximately 42 percent of adults in 1965 to 18 percent today, smoking is still the leading cause of premature disease and death in the country with nearly 500,000 deaths annually

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A plausible explanation is that prolonged smoking induces a series of structural and functional alterations in the airways, including epithelial injury, airway remodeling, excessive mucus production, and increased airway responsiveness 22