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However, GLS2 exhibits tumor heterogeneity and is found to be upregulated in specific malignancies, such as breast cancer, thereby promoting oncogenesis (37)

Specifically, betalains activate Nrf2 (nuclear factor-erythroid 2-related factor 2), the main regulator of the body's response to cellular damage and inflammation

Therefore, this paper strongly recommends that the Ethiopian government develop and enforce regulations on these environmental issues and implement intervention measures at the kebele level

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Furthermore, homocysteine-induced apoptosis is mainly mediated by induction DNA injury and energy depletion (Fan et al

doi: 10.3390/v10080392 34 KlopiI.PobernikM.MavriJ.DolencM