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A further generalization may be that BPC 157 effectiveness over the background of the NO-system[3,46,51,54], immobilized (L-NAME + L-arginine), (over)stimulated (L-arginine) or blocked (L-NAME), BPC 157 prevented MDA oxidative stress and normalized the NO tissue values

In IC and IC + RL rats, ischemia/reperfusion injury[9,10] increased and increased dramatically, respectively, whereas the MDA oxidative stress levels progressively increased, NO tissue values decreased with ligation and increased with ligation removal

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