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Statements Author contributions LB conceptualized the manuscript

Science 240, 924928

Whole blood and plasma samples of six JVC rats were collected at 0.05, 0.167, 0.5, 1, 2, 4, 8, 24, 48, and 72 h after administration (three males and three females at each time point) for the examination of radio pharmacokinetics of total plasma

ALAs antioxidant properties enhance blood flow, glucose uptake, and energy metabolism [155]

Rats of the BPH model group were orally administrated with or without PWE as aqueous solution at 0.6%, added with 1% sucrose, which was replenished every 2 days

Lipidomic analyses highlighted the similar presence of an aberrant lipid profile in the brain and in the peripheral tissues of diseased individuals (278)