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Thus, it can be hypothesized that the critical importance of Ca 2+ signaling in eryptosis is linked to the expulsion of the nucleus and the organelles (primarily mitochondria) in precursors of erythrocytes during erythropoiesis

[95] tested the hypothesis that dendritic density is higher in patients on lithium therapy than in those without lithium, using advanced MRI-based modeling of water diffusion in 41 medicated patients and 40 controls

It is also a cautionary illustration of how much context a mechanism carries: the best-characterized KPV effect depends on an intestinal transporter (PepT1) abundant in gut epithelium, which is one reason KPV has been explored mainly for oral delivery in bowel inflammation rather than as a general-purpose systemic anti-inflammatory

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icFSP1 also represses tumor growth and causes FSP1 undergo condensation in tumors [90]

PCS could promote the polarization of Kupffer cells from M1 to M2, reducing the inflammatory response