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Differential expression profile of lipid metabolism genes in KO livers following chronic alcohol feeding Hepatic quantitative real-time PCR analysis revealed that in KO mice fed control chow diet, genes promoting lipid synthesis ( Srebp1 , Fasn , Scd1 , and Fads1 ) were suppressed (Fig

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212 SAFETY AND EFFICACY OF DAPAGLIFLOZIN IN RECURRENT ASCITES: A PILOT STUDY Virendra Singh 1 , Arka De 2 , Rishav Aggarwal 1 , Shivani Chandel 1 , Akash Gandotra 2 and Naveen Dandia 1 , (1)Postgraduate Institute of Medical Education and Research, (2)Post Graduate Institute of Medical Education and Research Background: The pathophysiology of ascites in cirrhosis entails vasodilatation with the consequential activation of sympathetic nervous system and renin-angiotensin-aldosterone system, leading to retention of sodium and water

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