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Role of long-term antibiotics A meta-analysis of 12 studies that included 2151 patients showed that compared with control treatment those receiving long-term macrolides had reduced COPD exacerbations by 60% (3576%) 133

J Biol Chem 283(14):90899100

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The ATP-binding site in Cp1B where adenosine resides is partially covered by the lid domain with the P-loop and the A-loop from domain A 52 (Fig