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Immunogenicity (an unwanted immune reaction) is a stated risk in FDA materials on protein-based therapeutics

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Subsequent studies will need to clearly evaluate the safety and risk associated with more invasive measures that efficiently transduce or treat smaller areas, compared with broader, less-invasive means of distribution associated with limited brain penetrance due to the need to bypass the BBB

No accumulation of toxicity was detected in other healthy tissues in vivo, suggesting that porous silicon NPs have great potential in the field of drug delivery

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W formie iniekcji, zazwyczaj stosuje si roztwory zawierajce od 2 mg do 5 mg peptydu, podawane podskrnie lub dominiowo, w zalenoci od terapii