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In the future, the spatial distribution of fluorescence lifetimes across different retinal layers may further aid in classifying disease, as many diseases affect specific layers of the retina differently

Penrose JF, Austen KF (2000)

S3a) demonstrated that only Ferrostatin-1 (a ferroptosis inhibitor), but not Z-VAD-FMK (an apoptosis inhibitor) or Bafilomycin A1 (an autophagy inhibitor), significantly reduced the cell death induced by RSL3, suggesting that RSL3-induced cell death was attributed to ferroptosis rather than apoptosis or autophagy

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In addition to triggering the inflammatory response through lipotoxicity that causes hepatocyte injury or death, excess FFA in the liver can also exacerbate the inflammatory response through direct or indirect activation of TLR4

R., Revnic, F., Paltineanu, B