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For genetic deletion of FASN, FASN lox/lox MEFs were infected with adeno-Cre (Gene Transfer Vector Core, University of Iowa)

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(Reference Cai, Wang and Yu143) , in their meta-analysis investigating the relationship between Se exposure and the risk of various types of cancers, demonstrated an association between this micronutrient and a reduced risk of oesophageal cancer

As genetic knowledge of these diseases advances, associations between genes encoding mitochondrial proteins and clinical manifestations such as encephalopathy or intellectual delay, among others, are becoming clearer