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[20] Chemical and biological effects [edit] Chemically, oxidative stress is associated with increased production of oxidizing species or a significant decrease in the effectiveness of antioxidant defenses, such as glutathione

Cystine/glutamate antiporter (System Xc-), acting as a System Xc- on the cell membrane, regulates the upstream pathways of ferroptosis by primarily transporting extracellular cystine into the cell for GSH synthesis

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Hemoglobin and RBC membrane are the major targets of oxidative modifications when RBC antioxidant capacity is overwhelmed

Nanoparticles play a critical role by co-delivering LRAs and ARVs to the same reservoir sites, ensuring synchronized action [59]

It can also reduce the occurrence of tumors and atherosclerosis