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An experiment encompassing 27 healthy prehypertensive males subjected to varied combinations of sauna and exercise modalities demonstrated that the combination of endurance training followed by sauna immersion was the most efficacious in attenuating BP levels [99]

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Emerging clinical evidence indicates that serum CRP (human clinical study) is significantly increased in patients with DPN, 9193 while higher CRP level is inversely related to NCV ( P 0.8) in ROC analysis, supporting their potential use as non-invasive biomarkers