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Cardiovascular diseases mainly include coronary atherosclerotic heart disease, myocardial ischemia/reperfusion injury (IRI), and heart failure (HF)

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Kreimer A, Zeng H, Edwards MD, Guo Y, Tian K, Shin S, Welch R, Wainberg M, Mohan R , Sinnott-Armstrong NA, Li Y, Eraslan G, Amin TB, Tewhey R, Sabeti PC, Goke J, Mueller NS, Kellis M, Kundaje A, Beer MA, Keles S, Gifford DK, Yosef N

They are also based on relatively small study populations, and the researchers consistently emphasize that larger, longer-term trials are needed to confirm and expand these results

Together, they're the foundation of cellular health

41 In addition, the specific knockout or ablation of INSR in livers prevents insulin suppression of hepatic glucose production (HGP), 42,43 suggesting a direct role for INSR in hepatic IR