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Description

Science 339 , 826830 (2013)

ChemMedChem 4 , 15681582 (2009)

Fink RC, Scandalios JG

Catalysis of GPx is essentially following three distinct redox modifications of the Se at the center of the active site, in a triad of selenocysteine, glutamine, and tryptophan, which reduces GSH to GSSG [14, 19]