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The impact of these interactions on AR target gene expression is proportional to the enhancer-promoter contact frequency

2 Osteoarthritis: driven by synovitis and fibrosis Osteoarthritis is a highly prevalent musculoskeletal disorder and the most common form of arthritis

Ihubacter massiliensis is a key gut bacterium for human TMAO production Although a microbiome-based prediction model may be established to predict TMAO producer phenotypes, these selected microbial features represent correlations with TMAO productivity but lack of a cause-effect relationship

In about 1/10th of individuals with Epstein-Barr virus , Ross River virus , or Coxiella burnetti are more prone to develop symptoms meeting criteria for CFS (also known as post-infective fatigue syndrome), associated mainly with the severity of the infection

Although cytokines are mainly produced by the immune system, there is also an unclear link between neuroinflammation and these peripheral proinflammatory cytokines (201)

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