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Modifier 25 for Same-Day Evaluation and Management Modifier 25 must be appended to the E/M code, not to CPT 20610, when a significant and separately identifiable evaluation and management service is performed on the same date as the injection

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At concentrations ranging from 1 to 4 mcg of free base per mL, approximately 60 to 80 percent of lidocaine HCl becomes protein-bound