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1 (Pattern 1 (grades 13) and Pattern 2 (grades 46)

This selectivity is largely associated with donor substrate bioavailability

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Oxidation leads to the release of electrons that are accepted by oxidized nicotinamide adenine dinucleotides (NAD + or NADP + ), which are then reduced to NADH or NADPH 44

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Moreover, a substantial proportion of our data was obtained directly from primary ex vivo CLL samples or from proteomic and transcriptomic analyses performed without prior cell culture