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Promising effects of a multi-nutrient diet containing high Trp on disturbed behavior and reduced intestinal and CNS serotonin levels are reported in a murine model for ASD ( The Interaction Between Amino Acids and the Gut Microbiome in Relation to ASD Accumulating evidence has demonstrated a bidirectional communication between the brain and the gut, with the intestinal microbiota as a key factor in both health and disease (154, 155)

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