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Some studies have also pointed to interactions with the serotonergic and dopaminergic systems as a possible contributing factor, though this remains less well characterized than the neurotrophic pathway

doi:10.1038/s41467-021-20953-7 30

Kuratieva, S.P

The difference in side effect burden is real, and it is the primary reason the escalation process exists rather than starting everyone at the target dose

Disclaimer: The information in this blog post about mast cell activation syndrome and its connection to mold, is provided for general informational purposes only and may not reflect current medical thinking or practices