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75 These insights position epigenetic mechanisms as potential therapeutic targets for mitigating hyperglycemia-induced kidney damage

doi: 10.1016/j.jtemb.2018.02.015 [DOI] [PubMed] [Google Scholar] 64

Mechanistic studies in mice indicate that IL-17 contributes to hepatic inflammation by inducing CXCL10-dependent macrophage accumulation and enhancing collagen secretion by HSCs via STAT3-dependent pathways (119122)

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Oxidative Stress and Inflammation: Epitalons Antioxidant and Anti-Mutagenic Actions At the cellular level, aging isnt just about time - its about damage

Herein, we report that, via a TCF-independent mechanism, genotoxic stress induces the enrichment of -catenin in chromatin, where it forms a complex with ATM phosphorylated-JDP2 and PRMT5