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233 Sodium-glucose cotransporter-2 (SGLT2) inhibitors are commonly used for type 2 diabetes treatment, and in recent years, SGLT2 inhibitors canagliflozin has been shown to suppress IL-6 and IL-1 levels and MPO enzyme activity in the colon of UC rats by downregulating the expression of NF-B p65, thereby reducing colonic inflammatory cell infiltration and oxidative stress

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doi: 10.1309/hv6njvrqkk4qhm9f 126 HakimiAAReznikELeeCHCreightonCJBrannonARLunaAet al

Conversely, treatment with free DOX resulted in significant cell death in normal organs, particularly the heart, while the toxicity of DOX/LAAM GSH-CQDs was minimal (Supplementary Fig

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