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This protein-stabilizing action has been demonstrated across various riboflavin-responsive metabolic disorders, highlighting its dual role in both metabolic support and proteostasis maintenance

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Graham DI, Ford I, Adams JH, et al

This has been confirmed in permeability assays using fluorescent tracers, showing an MGO-induced increase in BMEC permeability for different particle sizes (390 Da to 150 kDa) [57, 62, 66]