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EC 50 : a Concentration (nM) of ferrostatin analogue required to achieve 50% viability against HT-1080 cells treated with 10 mM erastin

She had no risk factors to develop D-lactic acidosis, and the absence of neurological manifestations made this unlikely

A healthy heart plays a big role in overall fitness

The response of PeredoxDS was similar in wild-type, glr1 and trx1 trx2 cells, while NAPstarC showed no response in all cases (Supplementary Fig

Kozlowska A, Szostak-Wegierek D

Structural comparison of the LSM14 and EDC3 LSM domains indicates that EDC3 contains additional hydrophobic residues in the Nterminal region (Trp5 EDC3 ) and in the loop connecting strands 1 and 2 (Leu18 EDC3 ) that cap the hydrophobic pockets in its LSM domain, which would preclude 4ET association by steric clashes (Fig EV5A and B)