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Moreover, MZB entry and retention in the splenic marginal zone are tightly regulated by chemotactic molecules, such as C-X-C Motif Chemokine Ligand 13 (CXCL13) and sphingsoine-1-phosphate (S1P) 54

Cytokines play an important role in autoimmune responses and are often used as indicators to predict the occurrence and progression of diseases (29)

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Taken together, we expected that chronic exposure to DEHP at environmentally relevant doses would not be toxic, but would rather modulate cDC differentiation, which in turn would modify the magnitude of the resultant allergic response

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