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We found that simultaneous Cdkn1c hypomethylation and C/EBP overexpression in pancreatic -cells causes a synergistic decrease in pancreatic -cell mass

Lancet 367 , 10871100 (2006)

Nervous system of patients with epilepsy suffers severe damage because phagocytes rupture after penetrating the spinal cord tissue and invade the spinal fluid which further enters CSF

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These results confirm that targeting the AGE/RAGE signaling pathway can alleviate ferroptosis in the lung tissue during sepsis

Following an oral sucrose challenge, hCitrinmRNAtreated double KO mice further showed hepatic citrulline and plasma ammonium concentrations lower than those of double KO mice treated with a control mRNA, with concentrations of these metabolites maintained at levels similar to those measured in wildtype mice [118]