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However, these mice do not display the TDP-43 pathology that is present in almost all cases of ALS, and therefore they have been increasingly criticized as a disease model

Oncotarget 7(3):3548-58, 2016

The ability of m 6 A introduced into RNA to reduce cytokine and chemokine production during the development of the immune response has been demonstrated in numerous studies

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One study induced hemolytic hyperchromic anemia and impairment of hematopoiesis in the bone marrow of rabbits, and a decrease in blood-serum methylcobalamin was observed