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Cells (2020) 9:1940

Safety & Tolerability Preclinical Evidence : Animal studies indicate low toxicity and good tolerability at research doses

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doi: 10.1007/s10571-008-9297-7

Histidine also has properties that protect against oxidative stress and may play a role in tissue repair [2]

This restores programmed cell death in cancer cell lines including SH-SY5Y neuroblastoma and U937 histiocytic lymphoma at 1-10 nanomolar concentrations, while paradoxically stimulating healthy NIH-3T3 fibroblast growth