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126,127 Glucocorticoid resistance in COPD patients may also be related to the p38MAPK pathway through phosphorylated glucocorticoid receptor (GR) reducing GR translocation into the nucleus and DNA binding, impairing the GR function

Munib may recommend bloodwork to confirm deficiency and establish baseline levels, though testing isn't always necessary for patients with clear symptoms or known absorption issues

In these terms, indicative is the rat corneal ulcer successfully closed with the BPC 157 eye drops and maintained corneal transparency (Figure 14) (Masnec et al., 2015)