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Description

van der Burgh, et al

doi: 10.33073/pjm-2022-016 79 ZhouP.YaoQ.ZhaoQ.YangL.YuY.XieJ.et al

A Phase I study of FHD-609, a heterobifunctional degrader of bromodomain-containing protein 9, in patients with advanced synovial sarcoma or SMARCB1-deficient tumors

It is named according to the sequence of how the amino acid components are connected to each other

Mechanism: HGH Frag 176-191 shrinks cells via lipolysis

Our results explain the earlier observation that the mutation of LMP1 Y 384 YD to F 384 FD preserves LMP1s capacity to mediate CTAR2-dependent NF-B signalling, whereas the mutation to I 384 D abolishes its activity 37